MethComp summary report generated on 20/05/20 with pycoMeth 0.4.6

Overall summary
Total intervals Insufficient effect size Insufficient samples Non-significant pvalue Significant pvalue
340,171 322,452 7,774 2,015 7,930
Methylation category counts by sample for significant CpG intervals
Methylation log-likelihood ratio by significant CpG interval
Distribution of CpG methylation log-likelihood ratio for significant CpG intervals
Distribution of significant CpG intervals by chromosomic intervals
Top significant differentially methylated intervals
rank detailled report chromosome start end pvalue Number of nearby TSS closest tx id closest tx name closest tx biotype distance to tss
#1 report link 19 1465074 1471294 4.996094e-56 444 enst00000592486 c19orf25-211 retained_intron 5191
#2 report link 5 171313349 171317243 8.343135e-45 52 enst00000619056 ac091980.2-201 lncrna -3572
#3 report link 16 54936192 54939415 1.391326e-41 50 enst00000558156 ac106738.2-202 lncrna 0
#4 report link 5 141430472 141433184 1.117120e-30 222 enst00000613314 pcdhga12-202 protein_coding 0
#5 report link 1 145167533 145169830 3.227443e-28 58 enst00000621562 rnu1-153p-201 snrna 0
#6 report link 14 69571220 69573973 4.387150e-28 94 enst00000599174 ccdc177-201 protein_coding 898
#7 report link 7 149764357 149766480 9.399864e-28 112 enst00000484747 znf467-202 protein_coding 6739
#8 report link 4 1001583 1003754 1.929396e-27 271 enst00000514417 idua-211 retained_intron 0
#9 report link 17 61403712 61405954 4.050220e-27 51 enst00000586986 tbx2-204 processed_transcript 2768
#10 report link 8 140097670 140099673 2.289641e-26 47 enst00000631594 peg13-201 lncrna 870
#11 report link 17 72116370 72118672 5.337559e-26 164 enst00000653248 sox9-as1-220 lncrna 0
#12 report link 12 57737069 57739227 5.636185e-26 371 enst00000328568 agap2-202 protein_coding 0
#13 report link 19 13097401 13099852 1.451329e-25 358 enst00000590120 lyl1-202 retained_intron 2872
#14 report link 17 83133989 83135844 3.093195e-25 101 enst00000654400 ac139099.2-206 lncrna 0
#15 report link 20 20363429 20365644 6.003431e-25 60 enst00000623641 al161658.1-201 tec 0
#16 report link 16 693807 696068 7.062287e-25 490 enst00000562648 fbxl16-205 retained_intron 0
#17 report link 5 2748080 2750204 1.021193e-24 22 enst00000382611 irx2-202 protein_coding 1458
#18 report link 2 66445077 66447024 2.520449e-24 49 enst00000475239 meis1-208 processed_transcript 0
#19 report link 6 108174295 108176232 3.918777e-24 73 enst00000484978 nr2e1-204 processed_transcript 0
#20 report link 19 44756986 44758607 4.244485e-24 232 enst00000474300 bcl3-207 retained_intron 0
#21 report link 1 180234214 180236317 4.244485e-24 67 enst00000558139 lhx4-202 retained_intron -3916
#22 report link 7 155453612 155455178 5.703053e-24 82 enst00000419225 ac008060.3-201 lncrna 1921
#23 report link 19 46493059 46495487 8.508147e-24 236 enst00000377652 ac011484.1-201 lncrna 0
#24 report link 4 80201275 80203807 4.171388e-23 39 enst00000415738 prdm8-202 protein_coding -3772
#25 report link 18 57439921 57441962 4.652291e-23 65 enst00000481727 onecut2-201 processed_transcript 2414
#26 report link 17 64780064 64781774 7.563334e-23 161 enst00000579125 arhgap27p1-bptfp1-kpna2p3-202 lncrna 0
#27 report link 19 40612973 40614827 1.041624e-22 332 enst00000595118 ltbp4-212 retained_intron 0
#28 report link 6 137487832 137489432 1.852445e-22 66 enst00000367734 olig3-201 protein_coding 4962
#29 report link X 21655641 21659118 2.775756e-22 62 enst00000379499 klhl34-201 protein_coding 0
#30 report link 11 65646176 65647982 2.779823e-22 460 enst00000531339 sipa1-207 retained_intron 0
#31 report link 4 8856713 8858934 4.053512e-22 95 enst00000557144 ac116612.1-201 lncrna 1893
#32 report link 5 141491307 141492957 7.124041e-22 239 enst00000610789 pcdhgc5-202 protein_coding -2140
#33 report link 15 52794405 52796114 7.124041e-22 65 enst00000561401 onecut1-203 processed_transcript -3327
#34 report link 6 1392675 1394273 8.985000e-22 27 enst00000611664 mir6720-201 mirna -2264
#35 report link 9 127754034 127755653 1.312179e-21 333 enst00000629203 sh2d3c-213 protein_coding 0
#36 report link 22 27796653 27799585 4.619075e-21 78 enst00000424656 mn1-202 nonsense_mediated_decay 0
#37 report link 5 93571867 93573562 5.668270e-21 94 enst00000607831 nr2f1-as1-214 lncrna -524
#38 report link 22 19765660 19767542 1.423225e-20 237 enst00000484336 tbx1-205 retained_intron -581
#39 report link 20 46057007 46058998 1.893913e-20 203 enst00000637437 slc12a5-223 protein_coding 0
#40 report link 22 19722855 19724692 2.151569e-20 240 enst00000366425 gp1bb-201 protein_coding 0
#41 report link 17 79814738 79816386 2.220698e-20 147 enst00000667764 linc01977-202 lncrna 2697
#42 report link 7 989495 990877 2.345000e-20 166 enst00000415893 cyp2w1-203 protein_coding -2838
#43 report link 2 130692515 130693970 2.428471e-20 157 enst00000451977 klf2p3-201 processed_pseudogene 0
#44 report link 17 81527850 81529362 2.435948e-20 455 enst00000334850 fscn2-201 protein_coding 0
#45 report link X 1465367 1466722 3.844950e-20 59 enst00000534940 asmtl-206 protein_coding -11605
#46 report link 12 57726081 57727919 4.645517e-20 407 enst00000542466 agap2-as1-201 lncrna 0
#47 report link 5 177984160 177986165 6.760403e-20 250 enst00000308304 prop1-201 protein_coding 10077
#48 report link 19 3648956 3650054 1.139414e-19 215 enst00000592530 pip5k1c-206 processed_transcript 0
#49 report link 8 143278147 143279510 2.802632e-19 299 enst00000523031 mincr-205 lncrna 1339
#50 report link X 48826215 48827761 3.743694e-19 369 enst00000636362 eras-202 protein_coding 0
#51 report link 10 99521271 99522611 7.114760e-19 61 enst00000452494 al513542.1-201 lncrna 4337
#52 report link 1 976586 978571 8.130668e-19 445 enst00000479361 perm1-203 retained_intron 0
#53 report link 9 124014988 124016512 8.238015e-19 54 enst00000488674 lhx2-203 protein_coding 0
#54 report link 5 6773361 6774577 9.459863e-19 74 enst00000648399 linc02236-203 lncrna 1241
#55 report link 19 15457038 15458549 1.095324e-18 247 enst00000597025 rasal3-203 retained_intron 0
#56 report link 9 137450268 137452038 1.211388e-18 333 enst00000611474 mir7114-201 mirna -182
#57 report link 2 154698540 154699822 1.272188e-18 20 enst00000544049 kcnj3-203 protein_coding 0
#58 report link 19 17328027 17329755 1.361485e-18 351 enst00000600711 ano8-203 retained_intron 4974
#59 report link 4 8866964 8868473 1.984544e-18 96 enst00000506970 hmx1-202 protein_coding 3149
#60 report link 15 89408959 89410257 2.536323e-18 223 enst00000671447 mir9-3hg-253 lncrna -21627
#61 report link 7 767536 768780 3.024474e-18 153 enst00000403952 dnaaf5-202 protein_coding 0
#62 report link 22 23838197 23839612 3.179944e-18 216 enst00000404056 derl3-203 protein_coding 0
#63 report link 16 49277180 49278574 3.816398e-18 105 enst00000655430 ac044798.3-201 lncrna -1601
#64 report link 17 28384274 28385453 4.005198e-18 348 enst00000585453 sarm1-207 retained_intron 0
#65 report link 7 27141823 27143630 5.531442e-18 135 enst00000520854 hoxa5-202 processed_transcript 0
#66 report link 5 3601878 3603265 5.531442e-18 10 enst00000559410 ac016595.1-201 lncrna -1690
#67 report link 17 48550301 48551868 6.191839e-18 222 enst00000465846 hoxb-as3-203 lncrna -671
#68 report link 15 65395552 65397126 9.472275e-18 166 enst00000559327 igdcc4-204 retained_intron 0
#69 report link 2 176066755 176068252 1.083590e-17 71 enst00000308618 evx2-201 protein_coding 15661
#70 report link 1 3062986 3064284 1.257167e-17 77 enst00000321399 prdm16-dt-202 lncrna 0
#71 report link 3 194396715 194398455 1.257167e-17 208 enst00000401815 gp5-201 protein_coding 0
#72 report link 16 54288263 54289879 1.442988e-17 35 enst00000616682 ac018553.1-201 lncrna 1086
#73 report link 5 3599098 3600332 1.671181e-17 10 enst00000559410 ac016595.1-201 lncrna 0
#74 report link 19 58355910 58357548 2.262043e-17 311 enst00000596636 ac012313.3-203 lncrna 0
#75 report link 10 93059948 93061756 2.654166e-17 49 enst00000624358 cyp26c1-201 nonsense_mediated_decay 0
#76 report link 15 89378319 89379811 2.654166e-17 214 enst00000558754 mir9-3hg-205 lncrna 0
#77 report link 18 5890207 5891836 2.833590e-17 92 enst00000383490 tmem200c-201 protein_coding 268
#78 report link 21 46160485 46162232 3.102599e-17 164 enst00000397746 ftcd-203 protein_coding -4906
#79 report link 16 2236530 2238140 3.428700e-17 605 enst00000564055 ac009065.2-201 lncrna 0
#80 report link 10 86363012 86364273 6.805054e-17 36 enst00000464741 grid1-202 nonsense_mediated_decay 2220
#81 report link 10 133166368 133167794 7.336738e-17 146 enst00000368571 kndc1-202 protein_coding 0
#82 report link 5 177366903 177367884 7.452456e-17 281 enst00000511890 rgs14-209 protein_coding 0
#83 report link 16 88634016 88635175 1.134200e-16 196 enst00000244241 il17c-201 protein_coding 3397
#84 report link 16 67652623 67654020 1.297452e-16 520 enst00000602924 carmil2-211 retained_intron 0
#85 report link 15 82679964 82681226 1.603421e-16 189 enst00000666894 ap3b2-225 protein_coding 0
#86 report link 16 912164 913539 1.848945e-16 460 enst00000564460 al008727.1-201 lncrna -6940
#87 report link 19 1070971 1072321 2.129038e-16 483 enst00000543365 ac004151.1-208 protein_coding 0
#88 report link 15 89406944 89408372 2.308029e-16 221 enst00000671447 mir9-3hg-253 lncrna -19612
#89 report link 16 54281497 54282666 3.242314e-16 35 enst00000637770 ac018553.2-201 lncrna 2938
#90 report link 8 140099765 140101001 3.276346e-16 47 enst00000631594 peg13-201 lncrna 0
#91 report link 17 45428957 45431152 3.276346e-16 231 enst00000532891 arhgap27-214 protein_coding 0
#92 report link 19 47446997 47448525 4.884457e-16 179 enst00000601757 slc8a2-207 processed_transcript 0
#93 report link 1 203075448 203076659 5.490770e-16 148 enst00000594572 ppfia4-206 processed_transcript 0
#94 report link 17 45240959 45242226 6.119676e-16 292 enst00000587534 ac008105.1-201 lncrna 0
#95 report link 2 172080093 172081574 1.127113e-15 97 enst00000361609 dlx1-202 protein_coding 3166
#96 report link 1 1332513 1333703 1.146033e-15 466 enst00000339381 tas1r3-201 protein_coding -1233
#97 report link 19 17841311 17842723 1.188005e-15 287 enst00000528705 jak3-206 retained_intron 0
#98 report link 19 5058595 5059854 1.234154e-15 139 enst00000589104 kdm4b-208 retained_intron 10764
#99 report link 8 9898069 9899160 1.357140e-15 52 enst00000518557 linc00599-202 lncrna 2040
#100 report link 10 48450148 48451244 1.589073e-15 73 enst00000477708 arhgap22-210 protein_coding 383
#101 report link 1 43348388 43349760 1.686134e-15 243 enst00000671634 al139289.2-201 lncrna 0
#102 report link 17 61456303 61457574 1.955182e-15 59 enst00000642491 tbx4-207 protein_coding 0
#103 report link 1 90835271 90836499 1.955182e-15 56 enst00000670363 linc02609-222 lncrna 0
#104 report link 2 156319615 156320997 2.089950e-15 42 enst00000634100 ac074099.1-201 lncrna 0
#105 report link 12 80707849 80709118 2.089950e-15 52 enst00000228641 myf6-201 protein_coding -215
#106 report link 19 46648377 46650496 2.333428e-15 242 enst00000300875 dact3-201 protein_coding 4161
#107 report link 19 18777071 18778254 2.870257e-15 322 enst00000612179 comp-204 retained_intron 8781
#108 report link X 3346387 3347488 2.870257e-15 57 enst00000217939 mxra5-201 protein_coding 0
#109 report link 3 50275125 50277017 2.977555e-15 348 enst00000416295 sema3b-201 retained_intron -491
#110 report link 10 75395143 75397856 3.152121e-15 104 enst00000418818 ac010997.3-201 lncrna 3390
#111 report link 12 132270984 132272270 3.207868e-15 176 enst00000535208 galnt9-205 processed_transcript 2948
#112 report link 10 92690986 92692269 3.707441e-15 53 enst00000492654 hhex-203 protein_coding 0
#113 report link 1 18482252 18483305 5.804665e-15 27 enst00000400664 klhdc7a-201 protein_coding -1270
#114 report link 6 3224545 3225483 6.596106e-15 158 enst00000259818 tubb2b-201 protein_coding 2170
#115 report link 22 50719863 50721434 6.893250e-15 235 enst00000659388 shank3-204 protein_coding 8138
#116 report link 7 27251341 27252745 7.694556e-15 148 enst00000518886 evx1-203 processed_transcript -3973
#117 report link 1 217137129 217138574 8.637620e-15 32 enst00000366940 esrrg-207 protein_coding 0
#118 report link 19 13962302 13964169 9.402402e-15 214 enst00000588520 rfx1-203 retained_intron 0
#119 report link 5 73230217 73231331 9.402402e-15 92 enst00000427584 ac116345.1-203 lncrna -16235
#120 report link 19 8525815 8527115 9.501551e-15 181 enst00000596245 myo1f-206 retained_intron 0
#121 report link 7 102494140 102495276 1.025853e-14 140 enst00000488284 rasa4b-205 retained_intron 0
#122 report link 12 132835523 132836850 1.038243e-14 205 enst00000516270 rnu6-327p-201 snrna -23
#123 report link 13 50132274 50133978 1.180823e-14 101 enst00000618151 al137060.3-201 lncrna -6458
#124 report link 16 1019132 1020232 1.202605e-14 491 enst00000599946 ac009041.1-202 lncrna -18206
#125 report link 16 55330647 55332251 1.352712e-14 86 enst00000573934 ac109462.2-201 lncrna 104
#126 report link 13 114043702 114044738 1.424317e-14 102 enst00000542651 rasa3-202 processed_transcript -7509
#127 report link 5 93570321 93571592 1.472907e-14 94 enst00000607831 nr2f1-as1-214 lncrna 0
#128 report link 5 11384413 11385577 1.576431e-14 11 enst00000495388 ctnnd2-203 processed_transcript 0
#129 report link 13 113729703 113730407 1.591856e-14 107 enst00000545304 grk1-202 processed_transcript -3217
#130 report link 17 74356576 74357824 1.622335e-14 159 enst00000375366 btbd17-201 protein_coding 4044
#131 report link 19 48442368 48444808 1.903455e-14 317 enst00000598711 grwd1-202 protein_coding 1033
#132 report link 12 54018428 54019691 2.000113e-14 253 enst00000562848 ac012531.1-201 lncrna 219
#133 report link 11 118609436 118611360 2.000113e-14 383 enst00000532639 phldb1-221 protein_coding 0
#134 report link 11 979911 980652 2.163752e-14 407 enst00000527917 ap2a2-211 retained_intron 4732
#135 report link 20 40682660 40683906 2.261223e-14 35 enst00000373313 mafb-201 protein_coding 5330
#136 report link 8 902134 903249 2.344954e-14 47 enst00000633456 ac026950.2-201 lncrna -9022
#137 report link 1 16646922 16648717 2.381343e-14 174 enst00000457982 mst1p2-201 unprocessed_pseudogene -1300
#138 report link 2 70888459 70889814 2.734099e-14 132 enst00000449073 linc01143-201 lncrna -588
#139 report link 3 9945833 9948110 3.322533e-14 316 enst00000431558 prrt3-as1-201 lncrna 0
#140 report link 19 49337904 49339149 3.455268e-14 497 enst00000594743 cd37-206 protein_coding -689
#141 report link 19 7868132 7870134 3.455268e-14 281 enst00000597156 ac010336.3-201 lncrna 427
#142 report link 8 41566734 41567976 4.229248e-14 83 enst00000665362 ac009630.4-201 lncrna 0
#143 report link 7 102593401 102594445 4.354627e-14 161 enst00000522223 rasa4-213 retained_intron 0
#144 report link 21 39385121 39386159 4.371913e-14 169 enst00000380713 get1-202 protein_coding 0
#145 report link 13 99996875 99998262 4.483300e-14 66 enst00000564841 linc00554-201 lncrna 0
#146 report link 13 113820374 113821613 4.814629e-14 136 enst00000608763 gas6-204 retained_intron 1581
#147 report link 2 44944047 44945194 6.608508e-14 31 enst00000419364 six3-as1-201 lncrna -2174
#148 report link 5 179974119 179975388 7.404284e-14 255 enst00000649184 ac010285.3-201 lncrna 0
#149 report link 6 10417025 10418033 8.173364e-14 127 enst00000490875 tfap2a-217 processed_transcript 0
#150 report link 17 61454234 61455475 9.540085e-14 58 enst00000240335 tbx4-201 protein_coding 971
#151 report link 2 219447906 219449258 1.198927e-13 376 enst00000462545 speg-213 processed_transcript 1412
#152 report link 14 56797809 56798963 1.242538e-13 87 enst00000554845 otx2-205 protein_coding 6685
#153 report link 19 18869785 18870857 1.256534e-13 333 enst00000600689 upf1-210 retained_intron -6852
#154 report link 7 128915264 128916729 1.258284e-13 147 enst00000469533 ac025594.1-201 unprocessed_pseudogene -1201
#155 report link 17 44314868 44316217 1.566190e-13 279 enst00000588097 rundc3a-as1-202 lncrna 0
#156 report link 16 4380941 4382016 1.576936e-13 301 enst00000304735 vasn-201 protein_coding -9093
#157 report link 19 6475043 6476116 1.600528e-13 254 enst00000590818 dennd1c-210 retained_intron 99
#158 report link 2 104866992 104868029 1.663773e-13 108 enst00000454183 linc01159-203 lncrna 0
#159 report link 10 43395730 43397662 1.691872e-13 90 enst00000443950 hnrnpf-204 protein_coding 0
#160 report link 11 113314191 113315414 2.237301e-13 107 enst00000524580 ttc12-214 protein_coding 0
#161 report link 8 144547649 144548633 2.241235e-13 372 enst00000528810 arhgap39-203 processed_transcript -1985
#162 report link 2 236159308 236160358 2.620513e-13 42 enst00000384322 ac079135.1-201 misc_rna -6136
#163 report link 5 159104866 159105808 3.275587e-13 51 enst00000624206 ac134043.3-201 tec 572
#164 report link 13 99988942 99990064 3.334819e-13 69 enst00000481565 zic2-204 processed_transcript -3448
#165 report link 6 35317842 35318953 3.459224e-13 117 enst00000468102 def6-203 processed_transcript -234
#166 report link 11 128689675 128690759 4.114077e-13 60 enst00000527767 fli1-204 protein_coding 2223
#167 report link 10 101778627 101780425 4.358441e-13 119 enst00000618991 fgf8-207 protein_coding 0
#168 report link 11 60950585 60952014 4.466003e-13 280 enst00000541505 slc15a3-207 nonsense_mediated_decay 0
#169 report link 6 27830671 27831771 4.911564e-13 109 enst00000611927 h4c12-201 protein_coding 0
#170 report link 17 31008224 31009540 5.419866e-13 150 enst00000579692 ac138207.8-201 processed_transcript 0
#171 report link X 40091300 40092577 5.653582e-13 56 enst00000673391 bcor-215 protein_coding 4035
#172 report link 15 93065800 93066857 6.298624e-13 116 enst00000557561 ac087641.1-201 transcribed_processed_pseudogene 0
#173 report link 12 49263835 49265711 6.819882e-13 355 enst00000549023 ac010173.1-201 lncrna 0
#174 report link 14 73718430 73719600 7.191660e-13 203 enst00000478847 elmsan1-209 retained_intron 2024
#175 report link 1 229407010 229408217 7.627841e-13 58 enst00000516242 rn7skp276-201 misc_rna 2550
#176 report link 19 53554050 53555123 7.909227e-13 256 enst00000648511 znf331-225 protein_coding 0
#177 report link 7 157500761 157501976 9.238492e-13 62 enst00000669906 ac006372.1-202 lncrna 0
#178 report link 10 2935661 2936694 9.238492e-13 64 enst00000419388 ac026396.1-201 processed_pseudogene 0
#179 report link 2 104863596 104864466 9.699456e-13 108 enst00000454183 linc01159-203 lncrna 3030
#180 report link 6 26188238 26189254 9.699456e-13 204 enst00000614247 h4c4-201 protein_coding 0
#181 report link 5 3606229 3607148 9.722723e-13 10 enst00000559410 ac016595.1-201 lncrna -6041
#182 report link 17 45261651 45262576 1.042803e-12 289 enst00000588866 spata32-203 nonsense_mediated_decay 0
#183 report link 2 63059286 63060202 1.074069e-12 86 enst00000476383 otx1-204 retained_intron -8435
#184 report link 15 28454584 28455597 1.074069e-12 94 enst00000564639 ac091304.2-201 unprocessed_pseudogene 2186
#185 report link 5 141414667 141415625 1.078314e-12 219 enst00000398610 pcdhga10-201 protein_coding -1491
#186 report link 7 150322740 150324008 1.092631e-12 168 enst00000359623 lrrc61-202 protein_coding 0
#187 report link 5 173228696 173229703 1.132244e-12 100 enst00000521552 rpl7ap33-201 processed_pseudogene -2273
#188 report link 12 57224680 57225762 1.151294e-12 399 enst00000556825 shmt2-226 nonsense_mediated_decay 3811
#189 report link 17 79802607 79803543 1.175347e-12 147 enst00000485449 cbx8-204 processed_transcript -924
#190 report link 16 31475670 31477781 1.204256e-12 259 enst00000564804 tgfb1i1-209 nonsense_mediated_decay -2230
#191 report link 7 27113387 27114325 1.216292e-12 137 enst00000522193 hoxa-as2-208 lncrna 0
#192 report link 3 50364514 50365648 1.237700e-12 305 enst00000606259 z84492.1-201 lncrna 0
#193 report link 7 5295984 5297370 1.455141e-12 119 enst00000439491 slc29a4-205 processed_transcript 1959
#194 report link 6 137495170 137496226 1.455141e-12 65 enst00000367734 olig3-201 protein_coding -776
#195 report link 4 576907 578189 1.467657e-12 215 enst00000666138 ac116565.1-204 lncrna 0
#196 report link 1 90719323 90720202 1.482171e-12 55 enst00000660766 ac092805.1-201 lncrna 0
#197 report link 7 44962443 44963350 1.564778e-12 155 enst00000568457 ac004847.1-201 lncrna -1534
#198 report link 16 67165262 67166195 1.798965e-12 460 enst00000517680 hsf4-202 retained_intron 0
#199 report link 11 22340923 22341888 2.008184e-12 41 enst00000534115 slc17a6-202 retained_intron 1089
#200 report link 7 25852165 25853174 2.204710e-12 63 enst00000666265 ac018706.1-201 lncrna -20256

Source file: /hps/research1/birney/users/adrien/analyses/cancer_DNA_promethion/run_1_2_3_4/DNA_pipeline_2/results/methylation/pycometh_meth_comp_CGI_3/out.tsv.gz

MD5 hash: 9aa0e3f69cb4e12345c3758eb68a5efc